Papular mycosis fungoides: Six new cases and association with chronic lymphocytic leukemia

Table 3 Frequency of B-cell chronic lymphocytic leukemia occurring after a diagnosis of cutaneous T cell lymphoma

Ref.	Cohort	No. patients (Dx)	No. secondary B-CLL (%)
Olsen et al[27]	One institution	63 (CTCL)	0 (0)
Kantor et al[28]	One institution	519 (MF)	2 (0.39)
Väkevä et al[29]	Finnish cancer registry	319 (MF/SS)	1 (0.3)
Barzilai et al[24]	Two institutions	398 (MF)	2 (0.50)1
Huang et al[30]	One institution	429 (MF/SS)	1 (0.23)
Huang et al[30]	SEER-9 registry	1798 (MF/SS)	0 or 4 (0 or 0.22)2
Hallerman et al[31]	One institution	62 (CTCL)	0 (0)
Brownell et al[32]	One institution	672 (CTCL)	0 (0)
Hodak et al[33]	One institution	343 (MF)	2 (0.59)
Hodak et al[33]	Israeli population registry	683 (MF)	1 (0.15)
Lindahl et al[34]	Population-based	386 (MF)	0 (0)3
Current study	SEER-9 registry	3,977 (MF)	10 (0.25)

¹One case with B-CLL preceding MF was excluded;

²Surveillance, Epidemiology, and End Results (SEER)-9 Cohort between 1984 through 2001 included 4 cases of leukemia, not defined;

³The 2 cases of hematologic cancer exclusive of non-Hodgkin lymphoma in this cohort were not B-CLL (Lindahl, personal communication, 2016). MF: Mycosis fungoides; SS: Sézary syndrome; CTCL: Cutaneous T cell lymphoma; B-CLL: B cell chronic lymphocytic leukemia; Dx: Diagnostic groups in cohort.