Yellow urticaria in a patient with decompensated alcoholic cirrhosis triggered by intravenous albumin infusion: A case report

Table 2 Summary of previously published cases of yellow urticaria

Ref.	Year	Age/sex	Underlying condition	Peak bilirubin (mg/dL)	Urticaria trigger	Treatment
Clarke[4]	1969	Adult/male	Hepatic cirrhosis	Elevated (NR)	Idiopathic	Antihistamines
Nava Cruz et al[2]	2017	57 years/female	Biliary pancreatitis	8.4	Idiopathic	Antihistamines
Combalia et al[1]	2017	63 years/male	Cirrhosis	9.3	Drug	Antihistamines
Combalia et al[1]	2017	38 years/female	AIH/PBC overlap	7.8	Idiopathic	Antihistamines
Çakıcı et al[3]	2021	Adult/NR	Viral hepatitis B	5.9	Idiopathic	Antihistamines
Mendes et al[10]	2018	Adult/NR	ARV-induced liver injury	4.5	Drug (ARV)	Cessation + antihistamines
Hardy et al[9]	2022	67 years/male	End-stage liver disease	12.1	FFP transfusion	Antihistamines
Kalsi et al[6]	2024	Adult/NR	Acalabrutinib hepatotoxicity	6.8	Drug	Cessation + steroids
Toujani et al[8]	2023	33 years/female	AIH + PBC overlap	6.2	Idiopathic	Antihistamines
Gao et al[7]	2025	Adult/NR	Uncommon aetiology (NR)	NR	Idiopathic	Antihistamines
Present case	2025	70 years/male	Decompensated alcoholic cirrhosis (CPC 11)	10.5 (direct 7.2)	IV albumin (anaphylactoid)	IV hydrocortisone + chlorpheniramine + emollients

AIH: Autoimmune hepatitis; ARV: Antiretroviral; CPC: Child-Pugh Class; FFP: Fresh frozen plasma; NR: Not reported; PBC: Primary biliary cholangitis; IV: Intravenous.