Long-term persistence comparison between guselkumab and secukinumab for the treatment of psoriasis

doi:10.5314/wjd.121180

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World Journal of Dermatology

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2218-6190

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Dermatol. Sep 16, 2026; 12(1): 121180
Published online Sep 16, 2026. doi: 10.5314/wjd.121180

Table 1 Demographic and clinical characteristics of the patients included in the study, n (%)/median (inter-quartile range)/median ± inter-quartile range

	Secukinumab	Guselkumab	P value
Number of patients	87 (58.4)	62 (41.6)	-
Age (years)	53.7 (11.8-18.5)	50.1 (11.2-17.9)	NR
Male sex	40 (46.0)	41 (66.1)	0.023
PAS	15.0 (12.1-17.9)	15.4 (13.7-17.1)	NR
DLQI	12.9 (8.6-17.2)	12.4 (4.6-20.2)	NR
Non-Naïve	43 (49.4)	44 (70.9)	0.014
Previous lines of treatment	1.4 ± 0.8	1.9 ± 0.9	NR

P values calculated using χ² test for categorical variables. DLQI: Dermatology life quality index; PASI: Psoriasis Areas and Severity Index, IQR: Inter-quartile range; NR: Not reported.

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Citation: Borrás-Blasco J, Valcuende-Rosique A, Alcala R, Cornejo-Uixeda S. Long-term persistence comparison between guselkumab and secukinumab for the treatment of psoriasis. World J Dermatol 2026; 12(1): 121180
URL: https://www.wjgnet.com/2218-6190/full/v12/i1/121180.htm
DOI: https://dx.doi.org/10.5314/wjd.121180

Borrás-Blasco J, Valcuende-Rosique A, Alcala R, Cornejo-Uixeda S. Long-term persistence comparison between guselkumab and secukinumab for the treatment of psoriasis. World J Dermatol 2026; 12(1): 121180 [DOI: 10.5314/wjd.121180]

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