NDRG2 gene copy number is not altered in colorectal carcinoma

Table 3 Alteration in copy numbers for the NDRG2 and MYC genes in colorectal tissue

Colorectal tissue	Number of samples	Loss ddCt < 0.75	Unaltered ddCt 0.75-1.25	Gain ddCt > 1.25	Normal vs CRC
NDRG2 - 5’ end
Normal	8	1	7	0
CRC	40	2	29	9	P = 0.194a
NDRG2 - 3’ end
Normal	8	0	8	0
CRC	40	2	32	6	P = 0.470a
MYC
Normal	8	0	7	1
CRC	40	4	19	17	P = 0.135b

^aP value for comparison of ddCt values (supplementary table S2) in normal and CRC samples using an unpaired two-tailed t test;

^bP value for comparison of ddCt values (supplementary table S2) in normal and CRC samples using a Mann-Whitney test. ddCt: Delta delta Ct.