Tumor infiltrating lymphocytes in triple negative breast cancer receiving neoadjuvant chemotherapy

doi:10.5306/wjco.v7.i5.387

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Oct 10, 2016 (publication date) through Apr 28, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Oct 10, 2016; 7(5): 387-394
Published online Oct 10, 2016. doi: 10.5306/wjco.v7.i5.387

Table 5 Relationship between percentage and absolute counting methodologies of tumor-infiltrating-lymphocyte subpopulations

Population of lymphocytes	n	rho²	P-value	P corrected value³
Pre-NAC
CD3	27	0.7182	< 0.001	< 0.004¹
CD4	17	0.5071	0.0378	0.1512
CD8	27	0.6064	0.0008	0.0032¹
FOXP3	26	0.7192	< 0.001	< 0.004¹
Post-NAC
CD3	55	0.7733	< 0.001	< 0.004¹
CD4	30	0.6129	0.0003	0.0012¹
CD8	55	0.7338	< 0.001	< 0.004¹
FOXP3	47	0.5387	0.0001	0.0004¹

¹P < 0.05;

²Spearman correlation coefficient test;

³Bonferroni correction. NAC: Neoadjuvant-chemotherapy.

Citation: Castaneda CA, Mittendorf E, Casavilca S, Wu Y, Castillo M, Arboleda P, Nunez T, Guerra H, Barrionuevo C, Dolores-Cerna K, Belmar-Lopez C, Abugattas J, Calderon G, De La Cruz M, Cotrina M, Dunstan J, Gomez HL, Vidaurre T. Tumor infiltrating lymphocytes in triple negative breast cancer receiving neoadjuvant chemotherapy. World J Clin Oncol 2016; 7(5): 387-394
URL: https://www.wjgnet.com/2218-4333/full/v7/i5/387.htm
DOI: https://dx.doi.org/10.5306/wjco.v7.i5.387