Dynamic role of myofibroblasts in oral lesions

doi:10.5306/wjco.v6.i6.264

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Dec 10, 2015; 6(6): 264-271
Published online Dec 10, 2015. doi: 10.5306/wjco.v6.i6.264

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Figure 4 Transdifferentiation of fibroblast into carcinoma associated fibroblast in oral squamous cell carcinoma. Mutual paracrine effect between oral cancer cells and normal fibroblasts is responsible for transdifferentiation of the latter into malignant fibroblasts. CAF: Carcinoma associated fibroblast; TGF-β: Transforming growth factor-β; B.V: Blood Vessels; E-M: Epithelial-mesenchymal.

Citation: Bagul N, Ganjre A, Goryawala S, Kathariya R, Dusane S. Dynamic role of myofibroblasts in oral lesions. World J Clin Oncol 2015; 6(6): 264-271
URL: https://www.wjgnet.com/2218-4333/full/v6/i6/264.htm
DOI: https://dx.doi.org/10.5306/wjco.v6.i6.264