Analysis of the Hox epigenetic code

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 3, Issue 4

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Clinical Oncology

ISSN

2218-4333

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Clin Oncol. Apr 10, 2012; 3(4): 48-56
Published online Apr 10, 2012. doi: 10.5306/wjco.v3.i4.48

Table 2 Known roles of Ras-superfamily GTPases in Caenorhabditis elegans: Homologs in humans

**C.elegansgene name**	Human homolog	Developmental role(s)
Ras/Rap/Ral family
let-60	K-Ras	Cell fate determination, oocyte meiotic maturation, sex myoblast migration, axon pathfinding, olfaction, response to microbacterium nematophilum infection
Rho family
rho-1	RhoA	Cytokinesis, hypodermal contraction, P cell migration, axon pathfinding
cdc-42	Cdc42	Cytokinesis, embryonic polarity, axon pathfinding
ced-10	Rac1	Gastrulation, cell migration (P cells, distal tip cells), cell corpse phagocytosis, neuronal migration, axon pathfinding, vulval morphogenesis
rac-2	Rac1	Neuronal migration, axon pathfinding
mig-2	Mtl	Cell migration (P-cells, distal tip cells, Q cells and descendants), neuronal migration, axon pathfinding, vulval morphogenesis
Rab family
rab-1	Rab1	Innate immunity gene expression
rab-3	Rab3	Synaptic vesicle trafficking and release
Arf/Sar family
arl-6	Arf6	Ciliary vesicle trafficking and Bardet-Beidl syndromes
evl-20	Arf2	Microtubule organization, vulval cell division, tissue morphogenesis
Ran family
ran-1	Ran	Nuclear trafficking, nuclear reassembly, Kinetechore association with the mitotic spindle

Citation: Ezziane Z. Analysis of the Hox epigenetic code. World J Clin Oncol 2012; 3(4): 48-56
URL: https://www.wjgnet.com/2218-4333/full/v3/i4/48.htm
DOI: https://dx.doi.org/10.5306/wjco.v3.i4.48

Ezziane Z. Analysis of the Hox epigenetic code. World J Clin Oncol 2012; 3(4): 48-56 [PMID: 22553504 DOI: 10.5306/wjco.v3.i4.48]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.