Correlation between the proportion of breast volume involved by locally advanced tumors and invasion of the skin and posterior structures

Table 1 Comparison between the attributes of 98 patients with T3N > 0M0 breast tumors and 120 patients with T4a-c, any N, M0 tumors

BC	T3N>0	%	T4a-c	%	P value
Age Mean	51	-	58	-	< 0.001
≥ 50%BV	23/98	24	65/120	54	< 0.001
WB	1/98	1	21/99	21	< 0.001
Grade III	51/82	62	51/84	61	0.874
ER> 0	36/63	57	38/67	57	1
PR> 0	29/63	46	31/67	46	1
ER/PR> 0	27/63	43	33/67	49	0.486
Her2+	25/58	42	21/60	35	0.455
Triple neg	13/59	22	17/60	28	0.528
LVI	6/33	18	11/40	28	0.403

BC: Breast cancers; BV: Breast volume; WB: Whole breast; ER: Estrogen receptor; PR: Progesterone receptor; Her2+: Epidermoid growth factor receptor 2; LVI: Lymphovascular invasion.