Review
Copyright ©2011 Baishideng Publishing Group Co.
World J Clin Oncol. Jun 10, 2011; 2(6): 245-261
Published online Jun 10, 2011. doi: 10.5306/wjco.v2.i6.245
Table 1 Performance characteristics of the sCD26 test
CohortnCRC risksCD26cut-off(ng/mL)CRC in sCD26+ patientsAdvanced adenomas in sCD26+ patientsPolyps in sCD26+ patientsOther findings in sCD26+ patientsSensitivitySpecificity
(%)(%)
1st Case-control study[89]175Diagnosed with CRC41099/110--6/110 Crohn´s; 1/110 GC90% (CRC)90% (CRC)
1st Case-finding study[97]170Average-risk410-8/212/21 diverticula--
2nd Case-finding study[95]2673Average- and increased-risk4102/1404/140246/140212/140 diverticula100% (CRC)189.9% (CRC)1
2nd Case-control study [94]299Increased-risk46027/11020/11013/11018/110 IBD; 18/110 non-IBD; 14/110 anemia, diarrhea, rectal bleeding81.8% (CRC); 58% (CN)72.3% (CRC); 75.5 (CN)