Rethinking treatment for non-metastatic deficient mismatch repair colorectal and small bowel cancers

Figure 5 Case 4. A: Coronal and axial abdominal computed tomography (CT) images and colonoscopy at diagnosis; B: Post-treatment abdominal CT and positron emission tomography/computed tomography after completion of neoadjuvant therapy; C: Right hemicolectomy specimen; D: Microscopy showing an ulcerated cecal tumour bed with fibroinflammatory changes and granulation tissue, without residual viable tumour cells, consistent with a complete pathological response. Reactive lymph node changes and extensive tumour necrosis related to treatment are also observed.