Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer

doi:10.5306/wjco.123351

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World Journal of Clinical Oncology

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2218-4333

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World J Clin Oncol. Aug 24, 2026; 17(8): 123351
Published online Aug 24, 2026. doi: 10.5306/wjco.123351

Table 6 Univariable and multivariable analysis of disease-free survival

Risk factors	Univariable analysis		Multivariate analysis
Risk factors	HR (95%CI)	P value	HR (95%CI)	P value
Age (per 10 years)	0.917 (0.717-1.173)	0.490	0.919 (0.712-1.187)	0.518
Sex (male/female)	1.091 (0.507-2.350)	0.823	-
BMI (kg/m²)	0.953 (0.851-1.068)	0.407	-
Smoking (yes/no)	1.168 (0.590-2.315)	0.626	-
Hemoglobin (g/L)	0.993 (0.980-1.005)	0.234	-
Degree of differentiation (poor/well)	1.358 (0.609-3.026)	0.454	-
Clinical tumor stage (III/II)	1.166 (0.572-2.377)	0.672	-
Number of IAC	0.692 (0.305-1.571)	0.379	-
Surgery type (TG/SG)	1.508 (0.741-3.069)	0.257	-
T-stage regression (yes/no)	0.599 (0.301-1.191)	0.144	0.623 (0.289-1.344)	0.228
N-stage regression (yes/no)	0.313 (0.157-0.627)	P < 0.05^a	0.314 (0.147-0.669)	P < 0.05^a
Tumor regression (CR and PR/SD and PD)	0.446 (0.207-0.961)	P < 0.05^a	-	-
Complications (yes/no)	1.996 (0.946-4.212)	0.070	3.189 (1.335-7.621)	P < 0.05^a

^aP < 0.05.

HR: Hazard ratio; CI: Confidence interval; BMI: Body mass index; IAC: Intra-arterial chemoembolization; TG: Total gastrectomy; SG: Subtotal gastrectomy; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease.

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Citation: Wu XX, Yang HD, Min J, Yuan C, Li LS, Zhang W, Tong Y. Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer. World J Clin Oncol 2026; 17(8): 123351
URL: https://www.wjgnet.com/2218-4333/full/v17/i8/123351.htm
DOI: https://dx.doi.org/10.5306/wjco.123351

Wu XX, Yang HD, Min J, Yuan C, Li LS, Zhang W, Tong Y. Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer. World J Clin Oncol 2026; 17(8): 123351 [DOI: 10.5306/wjco.123351]

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