Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer

doi:10.5306/wjco.123351

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World Journal of Clinical Oncology

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2218-4333

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World J Clin Oncol. Aug 24, 2026; 17(8): 123351
Published online Aug 24, 2026. doi: 10.5306/wjco.123351

Table 5 Univariable and multivariable analysis of overall survival

Risk factors	Univariate analysis		Multivariate analysis
Risk factors	HR (95%CI)	P value	HR (95%CI)	P value
Age (per 10 years)	0.949 (0.738-1.221)	0.684	0.949 (0.727-1.237)	0.697
Sex (male/female)	1.040 (0.481-2.251)	0.919	-
BMI (kg/m²)	0.978 (0.873-1.096)	0.697	-
Smoking (yes/no)	1.052 (0.526-2.106)	0.886	-
Hemoglobin (g/L)	0.995 (0.983-1.007)	0.422	-
Degree of differentiation (poor/well)	1.488 (0.663-3.337)	0.335	-
Clinical tumor stage (III/II)	1.181 (0.412-3.384)	0.757	-
Number of IAC	0.643 (0.268-1.547)	0.324	-	-
Surgery type (TG/SG)	1.388 (0.678-2.842)	0.369	-
T-stage regression (yes/no)	0.532 (0.264-1.069)	0.076	0.512 (0.232-1.131)	0.098
N-stage regression (yes/no)	0.314 (0.155-0.636)	P < 0.05^a	0.301 (0.138-0.655)	P < 0.05^a
Tumor regression (CR and PR/SD and PD)	0.470 (0.217-1.016)	0.055	-	-
Complications (yes/no)	1.807 (0.851-3.836)	0.123	3.123 (1.283-7.597)	P < 0.05^a

^aP < 0.05.

HR: Hazard ratio; CI: Confidence interval; BMI: Body mass index; IAC: Intra-arterial chemoembolization; TG: Total gastrectomy; SG: Subtotal gastrectomy; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease.

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Citation: Wu XX, Yang HD, Min J, Yuan C, Li LS, Zhang W, Tong Y. Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer. World J Clin Oncol 2026; 17(8): 123351
URL: https://www.wjgnet.com/2218-4333/full/v17/i8/123351.htm
DOI: https://dx.doi.org/10.5306/wjco.123351

Wu XX, Yang HD, Min J, Yuan C, Li LS, Zhang W, Tong Y. Neoadjuvant intra-arterial chemoembolization improves tumor pathological regression and survival in Borrmann type IV gastric cancer. World J Clin Oncol 2026; 17(8): 123351 [DOI: 10.5306/wjco.123351]

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