Genomic landscape and clinical actionability of renal cell carcinoma in an Indian cohort: A real-world targeted next-generation sequencing study

doi:10.5306/wjco.123328

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World Journal of Clinical Oncology

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2218-4333

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Aug 24, 2026; 17(8): 123328
Published online Aug 24, 2026. doi: 10.5306/wjco.123328

Table 1 Baseline patient and tumour characteristics of the study cohort (n = 48), n (%)/median (range)

Characteristic
Age at diagnosis (years)	58 (32-84)
Biological sex
Male	36 (75)
Female	12 (25)
Histological subtype
Clear cell RCC	39 (81.3)
Papillary RCC	5 (10.4)
Other/unclassified	4 (8.3)
AJCC clinical stage
Stage I	15 (31.25)
Stage II	6 (12.5)
Stage III	16 (33.3)
Stage IV	11 (22.9)
Nuclear grade (WHO/ISUP)
Grade I-II	33 (68.75)
Grade III	7 (14.58)
Grade IV	8 (16.6)
Tumour content in block (%)	80 (30-95)

RCC: Renal cell carcinoma; WHO/ISUP: World Health Organization/International Society of Urological Pathology.

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Citation: Talwar V, Jain A, Goel V, Agarwal B, Gupta P, Tripathi R, Rawal S, Mehta A. Genomic landscape and clinical actionability of renal cell carcinoma in an Indian cohort: A real-world targeted next-generation sequencing study. World J Clin Oncol 2026; 17(8): 123328
URL: https://www.wjgnet.com/2218-4333/full/v17/i8/123328.htm
DOI: https://dx.doi.org/10.5306/wjco.123328

Talwar V, Jain A, Goel V, Agarwal B, Gupta P, Tripathi R, Rawal S, Mehta A. Genomic landscape and clinical actionability of renal cell carcinoma in an Indian cohort: A real-world targeted next-generation sequencing study. World J Clin Oncol 2026; 17(8): 123328 [DOI: 10.5306/wjco.123328]

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