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Observational Study
Copyright: ©Author(s) 2026.
World J Clin Oncol. Jul 24, 2026; 17(7): 123983
Published online Jul 24, 2026. doi: 10.5306/wjco.123983
Table 2 Patient symptom burden characteristics
Symptom category
Symptom
Grade 1 (n)
Grade 2 (n)
Grade 3 (n)
Grade 4 (n)
Total (n)
Moderate-to-severe symptom proportion (%)
Gastrointestinal symptomsNausea3819726613.6
Vomiting441431626.5
Diarrhea49523598.5
Constipation332540626.5
Systemic symptomsFatigue27181767132.4
Fever491001601.7
Skin/mucosal symptomsOral mucositis416335311.3
Hand-foot syndrome391140547.4
Neurological symptomsPeripheral neuropathy3910615612.5
Headache2816635516.4


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