Multicenter nomogram integrating clinicopathological features for prognosis in stage II-III deficient/microsatellite instability-high rectal cancer

Table 1 Baseline clinicopathological characteristics of the patients

Patient characteristics		Number	Percentage
Age (years)	mean ± SD	53.82 ± 12.42
Age (years)	≥ 53	42	39.3%
	< 53	65	60.7%
Sex	Male	70	65.4%
	Female	37	34.6%
BMI (kg/m2)	mean ± SD	22.79 ± 3.38
MutL homolog 1	+	45	42.1%
	-	62	57.9%
PMS1 homolog 2	+	53	49.5%
	-	54	50.5%
MutS homolog 2	+	40	37.4%
	-	67	52.6%
MutS homolog 6	+	49	45.8%
	-	58	54.2%
Deficient mismatch repair protein	1	36	33.6%
	2	62	57.9%
	3	9	8.4%
T stage	1	1	0.9%
	2	3	2.8%
	3	87	81.3%
	4	16	15.0%
N stage	0	73	68.2%
	1	22	20.6%
	2	12	11.2%
AJCC TNM staging system	II	73	68.2%
	III	34	31.8%
LVI	Positive	23	21.5%
	Negative	84	78.5%
PNI	Positive	14	13.1%
	Negative	93	86.9%
CA19-9 (35 U/mL)	mean ± SD	47.2 ± 135.5
CEA (5 ng/mL)	mean ± SD	8.2 ± 26.0
CA19-9 (35 U/mL)	Elevated	18	16.8%
	Normal	87	81.3%
	Missing data	2	1.9%
CEA (5 ng/mL)	Elevated	28	26.2%
	Normal	77	72.0%
	Missing data	2	1.9%
Recurrence	Yes	21	19.6%
	No	86	80.4%

BMI: Body mass index; AJCC: American Joint Committee on Cancer; TNM: Tumor-node-metastasis; LVI: Lymphovascular invasion; PNI: Perineural invasion; CEA: Carcinoembryonic antigen; CA19-9: Cancer antigen 19-9.