Risk factors for postoperative pathological fractures in lower extremity soft tissue sarcoma patients undergoing limb-sparing surgery

doi:10.5306/wjco.119535

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Jun 24, 2026; 17(6): 119535
Published online Jun 24, 2026. doi: 10.5306/wjco.119535

Table 2 Multivariate Firth’s penalized Cox regression analysis for risk factors

Characteristic	Hazard ratio	95%CI	P value
Age	1.02	0.99-1.05	0.185
Arterial hypertension	1.99	0.72-5.44	0.166
Radiotherapy	3.16	0.57-17.45	0.116
Bone resection	3.20	1.32-7.77	0.007
Osteoporosis	6.01	1.39-25.94	0.037

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Citation: Horsch A, Baus C, Deisenhofer J, Lunz A, Geisbüsch A, Lehner B. Risk factors for postoperative pathological fractures in lower extremity soft tissue sarcoma patients undergoing limb-sparing surgery. World J Clin Oncol 2026; 17(6): 119535
URL: https://www.wjgnet.com/2218-4333/full/v17/i6/119535.htm
DOI: https://dx.doi.org/10.5306/wjco.119535

Horsch A, Baus C, Deisenhofer J, Lunz A, Geisbüsch A, Lehner B. Risk factors for postoperative pathological fractures in lower extremity soft tissue sarcoma patients undergoing limb-sparing surgery. World J Clin Oncol 2026; 17(6): 119535 [DOI: 10.5306/wjco.119535]

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