Risk factors for postoperative pathological fractures in lower extremity soft tissue sarcoma patients undergoing limb-sparing surgery

doi:10.5306/wjco.119535

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World Journal of Clinical Oncology

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2218-4333

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Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Jun 24, 2026; 17(6): 119535
Published online Jun 24, 2026. doi: 10.5306/wjco.119535

Table 1 Comparison of baseline characteristics between 3D-conformal radiotherapy and intensity-modulated radiotherapy groups, n (%)/median (interquartile range)

Characteristic	3D-CRT (n = 59)	IMRT (n = 71)
Age (years)	56 (45-72)	59 (47-71)
Male	39 (66)	35 (49)
Female	20 (34)	36 (51)
BMI	27.5 (24.7-32.2)	26.4 (24.0-28.3)
Max tumor diameter (cm)	11.0 (5.5-15.0)	9.8 (6.8-15.5)
Tumor size > 10 cm	30 (51)	32 (45)
R1-resection	12 (20)	15 (21)
G3-STS	37 (63)	35 (49)
Periosteal stripping	7 (12)	6 (8)
Bone resection	24 (41)	20 (28)
RT dose (Gy)	60 (50-60)	60 (50-66)
Arterial hypertension	23 (39)	27 (38)
Osteoporosis	0 (0)	4 (6)

BMI: Body mass index; STS: Soft tissue sarcomas; RT: Radiotherapy; IMRT: Intensity-modulated radiotherapy; CRT: Conformal radiotherapy.

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Citation: Horsch A, Baus C, Deisenhofer J, Lunz A, Geisbüsch A, Lehner B. Risk factors for postoperative pathological fractures in lower extremity soft tissue sarcoma patients undergoing limb-sparing surgery. World J Clin Oncol 2026; 17(6): 119535
URL: https://www.wjgnet.com/2218-4333/full/v17/i6/119535.htm
DOI: https://dx.doi.org/10.5306/wjco.119535

Horsch A, Baus C, Deisenhofer J, Lunz A, Geisbüsch A, Lehner B. Risk factors for postoperative pathological fractures in lower extremity soft tissue sarcoma patients undergoing limb-sparing surgery. World J Clin Oncol 2026; 17(6): 119535 [DOI: 10.5306/wjco.119535]

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