Anlotinib plus albumin-bound paclitaxel induction-maintenance for sorafenib-refractory radioiodine-refractory differentiated thyroid cancer: A case report and review of literature

Figure 5 Radiologic progression during sorafenib therapy. A and B: A computed tomography scan obtained in February 2022, following several months of firstline sorafenib treatment, shows extensive bilateral pulmonary metastases and a substantial increase in the rightsided pleural effusion compared with prior imaging (arrows). These findings, together with rising serum thyroglobulin levels and worsening respiratory symptoms, indicate progressive disease under sorafenib.