Identification of SRSF2 as a potential immunodiagnostic biomarker for osteosarcoma: A study based on focused protein microarray

doi:10.5306/wjco.v17.i5.119275

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World Journal of Clinical Oncology

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2218-4333

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. May 24, 2026; 17(5): 119275
Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.119275

Table 2 Optical density of autoantibodies of osteosarcoma, osteochondroma, and normal controls, median (25^th percentile-75^th percentile)

	OS	OC	NC	H	P value
GNA11	0.424 (0.295-0.705)	0.544 (0.324-0.962)	0.426 (0.357-0.506)	3.025	0.220
SRSF2	0.673 (0.524-0.845)	0.683 (0.315-1.051)	0.498 (0.311-0.793)	6.354	0.042
PIK3CA	0.727 (0.516-0.971)	0.708 (0.380-1.051)	0.827 (0.561-1.072)	3.846	0.146

GNA11: G-protein subunit alpha 11; SRSF2: Serine/arginine-rich splicing factor 2; PIK3CA: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; OS: Osteosarcoma; OC: Osteochondroma; NC: Normal control.

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Citation: Ma Y, Wan L, Zhang YY, Luo YG, Yang N, Pu FF, Khan MIU, Liu M, Liu JS, Li JT. Identification of SRSF2 as a potential immunodiagnostic biomarker for osteosarcoma: A study based on focused protein microarray. World J Clin Oncol 2026; 17(5): 119275
URL: https://www.wjgnet.com/2218-4333/full/v17/i5/119275.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i5.119275

Ma Y, Wan L, Zhang YY, Luo YG, Yang N, Pu FF, Khan MIU, Liu M, Liu JS, Li JT. Identification of SRSF2 as a potential immunodiagnostic biomarker for osteosarcoma: A study based on focused protein microarray. World J Clin Oncol 2026; 17(5): 119275 [DOI: 10.5306/wjco.v17.i5.119275]

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