Clinicopathological and prognostic relevance of nestin in low- and high-grade gliomas: An immunohistochemical study

doi:10.5306/wjco.v17.i5.118350

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World Journal of Clinical Oncology

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2218-4333

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. May 24, 2026; 17(5): 118350
Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.118350

Table 2 Correlation between nestin expression and clinicopathological parameters

	Nestin underexpression	%	Nestin overexpression	%	P value
Tumor grades	Low grade = 19	29.7	Low grade = 45	70.3	0.004
Tumor grades	High grade = 6	9.4	High grade = 58	90.6	0.004
Age (years)	> 40 = 31	34.8	> 40 = 58	65.2	0.054
Age (years)	< 40 = 7	17.9	< 40 = 32	82.1	0.054
Gender	Male = 25	29.4	Male = 60	70.6	0.92
Gender	Female = 13	30.2	Female = 30	67.8	0.92
Tumor site	Supratentorial = 32	29.6	Supratentorial = 76	70.4	0.973
Tumor site	Infratentorial = 6	30	Infratentorial = 14	70	0.973

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Citation: Nasir S, Ali A, Ullah I, Wazir S, Javaid I, Jalal SZ, Khan I, Mubarak M. Clinicopathological and prognostic relevance of nestin in low- and high-grade gliomas: An immunohistochemical study. World J Clin Oncol 2026; 17(5): 118350
URL: https://www.wjgnet.com/2218-4333/full/v17/i5/118350.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i5.118350

Nasir S, Ali A, Ullah I, Wazir S, Javaid I, Jalal SZ, Khan I, Mubarak M. Clinicopathological and prognostic relevance of nestin in low- and high-grade gliomas: An immunohistochemical study. World J Clin Oncol 2026; 17(5): 118350 [DOI: 10.5306/wjco.v17.i5.118350]

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