Integrated Chinese and Western medicine prolong survival in colorectal cancer with liver metastasis: A retrospective cohort study

doi:10.5306/wjco.v17.i5.118265

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. May 24, 2026; 17(5): 118265
Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.118265

Table 1 Comparison of baseline data between two cohorts, mean ± SD/n (%)

	Cohort A (n = 185)	Cohort B (n = 314)	t/χ²	P value
Age	62.47 ± 11.30	58.51 ± 10.33	3.89	< 0.01^a
Gender			0.60	0.44
Male	106 (57.30)	191 (60.83)
Female	79 (42.70)	123 (39.17)
Primary site			0.08	0.78
Right-side colon	57 (30.81)	93 (29.62)
Left-side colon	128 (69.19)	221 (70.38)
Local treatment of liver metastases¹			40.60	< 0.01^a
Yes	66 (35.68)	204 (64.97)
No	119 (64.32)	110 (35.03)
Gene type			0.81	0.67
RAS/BRAF wild type	83 (44.86)	141 (44.90)
RAS/BRAF mutation	87 (47.03)	154 (49.04)
No genetic testing	15 (8.11)	19 (6.05)
Site of metastasis			0.13	0.72
Liver metastasis only	73 (39.46)	129 (41.08)
Combined with extrahepatic metastasis	112 (60.54)	185 (58.92)

^aP < 0.01.

¹Local treatments include radiofrequency ablation, local interventional surgical resection, radiotherapy, and argon-helium knife therapy.

RAS: Rat sarcoma viral oncogene homolog; BRAF: B-Raf proto-oncogene, serine/threonine kinase.

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Citation: Bian JY, Sun YX, Wang LF, He WT, Liu CB, Wang XQ, Zhang T. Integrated Chinese and Western medicine prolong survival in colorectal cancer with liver metastasis: A retrospective cohort study. World J Clin Oncol 2026; 17(5): 118265
URL: https://www.wjgnet.com/2218-4333/full/v17/i5/118265.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i5.118265

Bian JY, Sun YX, Wang LF, He WT, Liu CB, Wang XQ, Zhang T. Integrated Chinese and Western medicine prolong survival in colorectal cancer with liver metastasis: A retrospective cohort study. World J Clin Oncol 2026; 17(5): 118265 [DOI: 10.5306/wjco.v17.i5.118265]

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