Hepatic resection in adolescent and young adult patients with hepatocellular carcinoma

doi:10.5306/wjco.v17.i5.117168

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. May 24, 2026; 17(5): 117168
Published online May 24, 2026. doi: 10.5306/wjco.v17.i5.117168

Table 3 Clinicopathological findings in the adolescent and young adult and non-adolescent and young adult groups

Variable	AYA group (n = 9)	Non-AYA group (n = 885)	P value
Age (year)	33.3	70.0	0.001
Sex (male/female)	5/4	679/197	0.125
BMI	21.6	26.9	0.875
HBV	6/3	114/733	0.001
HCV	0/9	367/483	0.006
LC	2	370	0.353
AFP in ng/mL	7971	4236	0.795
PIVKA-II in mAU/mL	6489	6483	0.999
Child-Pugh class: A/B/C	8/1/0	744/95/0	0.820
Partial hepatectomy: +/-	4/5	363/522	0.554
Laparoscopic hepatectomy: +/-	4/5	300/585	0.375
Vascular invasion: +/-	5/4	264/550	0.134
Tumor number as single/multiple	8/1	632/151	0.460
Tumor diameter in mm	79.3	44.3	0.002
pStage: I/II/III/IV	1/3/4/1	142/334/239/99	0.866
Operate time (min)	263	313	0.269
Operate bleeding (mL)	642	745	0.803
Surgical margin: +/-	0/9	82/686	0.456
Blood transfusion: +/-	¾	109/429	0.156
Postoperative hospital stays (days)	10.0	15.8	0.335
Morbidity: +/-	0/9	106/449	0.349

Data are shown as n (%), n, or mean, unless otherwise indicated. AFP: Alpha-fetoprotein; AYA: Adolescent and young adult; BMI: Body mass index; HBV: Hepatitis B virus; HCV: Hepatitis C virus; LC: Liver cirrhosis; PIVKA-II: Protein induced by vitamin K absence or antagonist-II; pStage: Pathological stage according to the Union for International Cancer Control (8^th edition).

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Citation: Ueda J, Taniai N, Yoshioka M, Matsushita A, Mizutani S, Kawano Y, Shimizu T, Kanda T, Murokawa T, Takata H, Furuki H, Aoki Y, Kawashima M, Irie T, Ono T, Haruna T, Yoshimori D, Endo K, Hamaguchi A, Yoshida H. Hepatic resection in adolescent and young adult patients with hepatocellular carcinoma. World J Clin Oncol 2026; 17(5): 117168
URL: https://www.wjgnet.com/2218-4333/full/v17/i5/117168.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i5.117168

Ueda J, Taniai N, Yoshioka M, Matsushita A, Mizutani S, Kawano Y, Shimizu T, Kanda T, Murokawa T, Takata H, Furuki H, Aoki Y, Kawashima M, Irie T, Ono T, Haruna T, Yoshimori D, Endo K, Hamaguchi A, Yoshida H. Hepatic resection in adolescent and young adult patients with hepatocellular carcinoma. World J Clin Oncol 2026; 17(5): 117168 [DOI: 10.5306/wjco.v17.i5.117168]

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