Overexpression of low-molecular-weight caldesmon is associated with aggressive phenotypes and epithelial-mesenchymal transition in breast cancer cells

Figure 6 Correlation between low-molecular-weight isoform of caldesmon immunohistochemical intensity and clinicopathological features of invasive breast carcinoma. Graph shows the correlation between the low-molecular-weight isoform of caldesmon (l-CAD) immunohistochemical scores in formalin-fixed, paraffin-embedded breast cancer and clinicopathological parameters. Positive correlation coefficients (> 0) indicate associations between l-CAD staining intensity and HER2-enriched breast cancer, lymphovascular invasion, and the presence of an in situ component. Negative correlation coefficients (< 0) indicate inverse associations between l-CAD expression and estrogen and progesterone receptor status.