Body mass index predicts low muscle mass in esophageal squamous cell carcinoma patients undergoing chemoradiotherapy

doi:10.5306/wjco.v17.i4.116601

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Apr 24, 2026; 17(4): 116601
Published online Apr 24, 2026. doi: 10.5306/wjco.v17.i4.116601

Table 3 Associations between body mass index and all-cause mortality in participants with sarcopenia

Characteristic	Model 1			Model 2			Model 3
Characteristic	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value
BMI (continuous)	0.923	0.879-0.970	0.001	0.94	0.891-0.992	0.023	0.941	0.892-0.993	0.025
BMI (categorical)
18.5 kg/m²	Reference	Reference	-	Reference	Reference	-	Reference	Reference	-
18.5-24.0 kg/m²	0.732	0.471-1.138	0.166	0.783	0.495-1.239	0.296	0.732	0.471-1.138	0.446
≥ 24.0 kg/m²	0.574	0.346-0.951	0.031	0.583	0.346-0.984	0.043	0.574	0.346-0.951	0.047
P for trend	-	-	< 0.001	-	-	0.017	-	-	0.02

Model 1: Unadjusted; Model 2: Adjusted for age, gender, Karnofsky performance score, smoking history, alcohol history; Model 3: Age, gender, Karnofsky performance score, smoking history, alcohol history, tumor location, radiotherapy dose, chemotherapy, T stage, N stage, glucose, total cholesterol, triglyceride. HR: Hazard ratio; BMI: Body mass index; CI: Confidence interval.

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Citation: Xiao L, Liu YD, Zhang X, Zhang SC, Lyu JH. Body mass index predicts low muscle mass in esophageal squamous cell carcinoma patients undergoing chemoradiotherapy. World J Clin Oncol 2026; 17(4): 116601
URL: https://www.wjgnet.com/2218-4333/full/v17/i4/116601.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i4.116601

Xiao L, Liu YD, Zhang X, Zhang SC, Lyu JH. Body mass index predicts low muscle mass in esophageal squamous cell carcinoma patients undergoing chemoradiotherapy. World J Clin Oncol 2026; 17(4): 116601 [DOI: 10.5306/wjco.v17.i4.116601]

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