Longitudinal microRNA profiles in breast cancer tissue and plasma: Associations with hormone receptors, response, and survival

Table 1 Clinicopathologic characteristics of breast tumors before and after neoadjuvant chemotherapy

Characteristics		Primary tumor, n = 38	Post-NACT, n = 35	P value
Stage (AJCC)	0	0	3	0.21
	I	0	1
	IIA	5	7
	IIB	15	8
	IIIA	10	8
	IIIB	7	7
	IIIC	1	1
Category T	0	0	3	0.54
	1	2	2
	2	27	21
	3	2	2
	4	7	7
Category N	0	4	11	0.14
	1	17	11
	2	16	12
	3	1	1
Ki-67 index, median (interquartile range)		25 (15.0-38.8)	22.5 (12.9-37.85)	0.645

American Joint Committee on Cancer stage, T category, and N category are shown as frequencies (n). Ki-67 expression is reported as median with interquartile range. Comparisons between pre- and post- neoadjuvant chemotherapy groups were performed using the Cochran-Armitage test for trend and Wilcoxon rank-sum test (P value). No statistically significant differences were observed between groups. AJCC: American Joint Committee on Cancer; NACT: Neoadjuvant chemotherapy.