PIGU overexpression and regulation of cellular biological functions in bladder cancer

doi:10.5306/wjco.v17.i3.117055

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Mar 24, 2026; 17(3): 117055
Published online Mar 24, 2026. doi: 10.5306/wjco.v17.i3.117055

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Figure 12 Identification of cell cycle-related hub genes. A: Protein interaction results from the String database visualized in Cytoscape; B: Hub genes with the strongest protein interactions identified by the Cytoscape algorithm using the cytoHubba module; color shading indicates interaction strength; C and D: Protein-protein interaction network analysis (C: The String database; D: GeneMANIA database); E: Heatmap showing PIGU correlations with 30 hub genes; F: Forest plot of COX regression analysis for 30 hub genes; G: Scatterplot showing PIGU correlations with identified genes PCNA, MCM2, RRM1, RRM2, and AURKA.

Citation: Li SH, Liu ZS, Chen YJ, Li JD, Wei L, Chen YY, Zhang W, Huang ZG, Chen ZD, Chen G, Wei DM, Mo ZN, Deng LL. PIGU overexpression and regulation of cellular biological functions in bladder cancer. World J Clin Oncol 2026; 17(3): 117055
URL: https://www.wjgnet.com/2218-4333/full/v17/i3/117055.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i3.117055

Li SH, Liu ZS, Chen YJ, Li JD, Wei L, Chen YY, Zhang W, Huang ZG, Chen ZD, Chen G, Wei DM, Mo ZN, Deng LL. PIGU overexpression and regulation of cellular biological functions in bladder cancer. World J Clin Oncol 2026; 17(3): 117055 [DOI: 10.5306/wjco.v17.i3.117055]

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