Metabolic axis of autophagy: A key player in tumor maintenance and opportunities for therapeutic exploitation

doi:10.5306/wjco.v17.i3.115094

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Mar 24, 2026; 17(3): 115094
Published online Mar 24, 2026. doi: 10.5306/wjco.v17.i3.115094

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Figure 1 The macroautophagy pathway and recycling of macromolecules. AKT: Protein kinase B; AMPK: Adenosine monophosphate-activated protein kinase; ATG: Autophagy-related protein; ATP: Adenosine triphosphate; LC3: Light chain 3; mTORC: Mechanistic target of rapamycin complex; PI3KC1: Phosphatidylinositol 3-kinase complex 1; PE: Phosphatidylethanolamine; ULK1: Unc-51 like autophagy activating kinase 1.

Citation: Garg M. Metabolic axis of autophagy: A key player in tumor maintenance and opportunities for therapeutic exploitation. World J Clin Oncol 2026; 17(3): 115094
URL: https://www.wjgnet.com/2218-4333/full/v17/i3/115094.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i3.115094

Garg M. Metabolic axis of autophagy: A key player in tumor maintenance and opportunities for therapeutic exploitation. World J Clin Oncol 2026; 17(3): 115094 [DOI: 10.5306/wjco.v17.i3.115094]

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