When to operate pancreatic intraductal papillary mucinous neoplasm: Literature review

Table 1 Histologic features of intraductal papillary mucinous neoplasms according to cell types

Histological subtype	Histological features	Associated carcinoma	Prognosis
Gastric	Foveolar-like cells, may be associated with intestinal metaplasia, low-grade dysplasia. Mainly branch duct	Ductal/tubular adenocarcinoma	Slightly better prognosis than PDC not associated with IPMNs
Intestinal	Tall columnar epithelium (villous adenoma like), low to high-grade dysplasia. Often main duct affected	Mucinous/colloid carcinoma	Better than PDC
Pancreatobiliary	Cuboidal cells, thin branching or complex papillae (cholangio-papillary like tumors). High-grade dysplasia often main duct affected	Ductal/tubular adenocarcinoma	Slightly better prognosis than PDC not associated with IPMNs
Oncocytic	Arborizing papillae	Rare	-

IPMNs: Intraductal papillary mucinous neoplasms; PDC: Pancreatic ductal carcinoma.