T cell exhaustion markers in hepatitis C virus-related hepatocellular carcinoma: Expression patterns and prognostic significance in an Egyptian cohort

doi:10.5306/wjco.v17.i2.114622

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Feb 24, 2026; 17(2): 114622
Published online Feb 24, 2026. doi: 10.5306/wjco.v17.i2.114622

Table 3 Liver function scores in hepatocellular carcinoma and cirrhosis groups, mean ± SD/n (%)

Parameter	HCC (n = 50)	Cirrhosis (n = 50)	t/χ²	P value
MELD	2.5 ± 1.0	2.56 ± 1.09	-0.287	0.774
Child-Pugh class			1.795	0.18
A	9 (18)	13 (26)
B	9 (18)	12 (24)
C	32 (64)	25 (50)

χ² for trend test for Child-Pugh class. t-test for Model for End-Stage Liver Disease adjusted for age to control for demographic confounders. MELD: Model for End-Stage Liver Disease; HCC: Hepatocellular carcinoma.

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Citation: Hasan AM, Ghanem SMFI, Othman AAA, Rashad MH, Nosair N, Elgamal R. T cell exhaustion markers in hepatitis C virus-related hepatocellular carcinoma: Expression patterns and prognostic significance in an Egyptian cohort. World J Clin Oncol 2026; 17(2): 114622
URL: https://www.wjgnet.com/2218-4333/full/v17/i2/114622.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i2.114622

Hasan AM, Ghanem SMFI, Othman AAA, Rashad MH, Nosair N, Elgamal R. T cell exhaustion markers in hepatitis C virus-related hepatocellular carcinoma: Expression patterns and prognostic significance in an Egyptian cohort. World J Clin Oncol 2026; 17(2): 114622 [PMID: 41810349 DOI: 10.5306/wjco.v17.i2.114622]

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