Gene and cytokine expression profiles of metastatic colorectal cancer patients post reovirus administration

doi:10.5306/wjco.v17.i2.113428

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Feb 24, 2026; 17(2): 113428
Published online Feb 24, 2026. doi: 10.5306/wjco.v17.i2.113428

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Figure 5 Depicts proposed interactions between reovirus and the phosphoinositide 3-kinase-alpha serine/threonine-protein kinase pathway. Reovirus results in alterations of PTENP1 and/or RICTOR to catalyze intracellular changes via the phosphoinositide 3-kinase-alpha serine/threonine-protein kinase pathway. The exact interactions between reovirus and the phosphoinositide 3-kinase-alpha serine/threonine-protein kinase pathway remain unclear. PI3K: Phosphoinositide 3-kinase; AKT: Threonine-protein kinase; VEGF: Vascular endothelial growth factor; PTEN: Phosphatase and tensin homolog.

Citation: Zweig V, Goel S, Maitra R. Gene and cytokine expression profiles of metastatic colorectal cancer patients post reovirus administration. World J Clin Oncol 2026; 17(2): 113428
URL: https://www.wjgnet.com/2218-4333/full/v17/i2/113428.htm
DOI: https://dx.doi.org/10.5306/wjco.v17.i2.113428

Zweig V, Goel S, Maitra R. Gene and cytokine expression profiles of metastatic colorectal cancer patients post reovirus administration. World J Clin Oncol 2026; 17(2): 113428 [PMID: 41810348 DOI: 10.5306/wjco.v17.i2.113428]

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