Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage

doi:10.5306/wjco.125097

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Oct 24, 2026; 17(10): 125097
Published online Oct 24, 2026. doi: 10.5306/wjco.125097

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Figure 1 Study flow diagram. The patients were identified from two sources: (1) The pathological database, searched using poorly cohesive carcinoma (PCC)-related keywords; and (2) The departmental follow-up registration system for non-PCC cases. PCC was further classified into signet ring cell carcinoma (SRC) (≥ 90%), mixed SRC/PCC-not otherwise specified (NOS) (10% < SRC < 90%), and PCC-NOS (≤ 10%). Cross-validation was used to ensure that no PCC cases were wrongly classified as non-PCC cases. PCC: Poorly cohesive carcinoma; SRC: Signet ring cell carcinoma; NOS: Not otherwise specified.

Citation: Zheng YH, Wang YY, Wang SC, Wang CJ, Shen YY, Cui JZ, Liu SM, Zhang YH, Zeng XQ, Zhao EH. Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage. World J Clin Oncol 2026; 17(10): 125097
URL: https://www.wjgnet.com/2218-4333/full/v17/i10/125097.htm
DOI: https://dx.doi.org/10.5306/wjco.125097

Zheng YH, Wang YY, Wang SC, Wang CJ, Shen YY, Cui JZ, Liu SM, Zhang YH, Zeng XQ, Zhao EH. Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage. World J Clin Oncol 2026; 17(10): 125097 [DOI: 10.5306/wjco.125097]

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