Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage

doi:10.5306/wjco.125097

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World Journal of Clinical Oncology

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2218-4333

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Retrospective Cohort Study

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World J Clin Oncol. Oct 24, 2026; 17(10): 125097
Published online Oct 24, 2026. doi: 10.5306/wjco.125097

Table 5 Clinicopathological features of signet ring carcinoma, signet ring carcinoma/poorly cohesive carcinoma-not otherwise specified, and poorly cohesive carcinoma-not otherwise specified after propensity score matching, n (%)

		Before PSM					After PSM
		SRC	SRC/PCC-NOS	PCC-NOS	P value	SMD	SRC	SRC/PCC-NOS	PCC-NOS	P value	SMD
n		70	171	133			56	56	56
Sex	Female	37 (52.857)	95 (55.556)	44 (33.083)	< 0.001	0.309	27 (48.214)	29 (51.786)	29 (51.786)	0.909	0.048
Sex	Male	33 (47.143)	76 (44.444)	89 (66.917)			29 (51.786)	27 (48.214)	27 (48.214)
Age	< 60	28 (40.000)	82 (47.953)	53 (39.850)	0.581	0.144	26 (46.429)	25 (44.643)	25 (44.643)	0.984	0.094
	60-74	36 (51.429)	74 (43.275)	65 (48.872)			27 (48.214)	27 (48.214)	26 (46.429)
	≥ 75	6 (8.571)	15 (8.772)	15 (11.278)			3 (5.357)	4 (7.143)	5 (8.929)
Stage	I	35 (51.471)	44 (26.347)	25 (19.380)	< 0.001	0.580	27 (48.214)	26 (46.429)	25 (44.643)	0.995	0.080
	II	12 (17.647)	24 (14.371)	18 (13.953)			8 (14.286)	8 (14.286)	10 (17.857)
	III	19 (27.941)	86 (51.497)	82 (63.566)			19 (33.929)	20 (35.714)	19 (33.929)
	IV	2 (2.941)	13 (7.784)	4 (3.101)			2 (3.571)	2 (3.571)	2 (3.571)

PSM: Propensity score matching; SRC: Signet ring carcinoma; PCC-NOS: Poorly cohesive carcinoma-not otherwise specified; SMD: Standardized mean difference.

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Citation: Zheng YH, Wang YY, Wang SC, Wang CJ, Shen YY, Cui JZ, Liu SM, Zhang YH, Zeng XQ, Zhao EH. Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage. World J Clin Oncol 2026; 17(10): 125097
URL: https://www.wjgnet.com/2218-4333/full/v17/i10/125097.htm
DOI: https://dx.doi.org/10.5306/wjco.125097

Zheng YH, Wang YY, Wang SC, Wang CJ, Shen YY, Cui JZ, Liu SM, Zhang YH, Zeng XQ, Zhao EH. Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage. World J Clin Oncol 2026; 17(10): 125097 [DOI: 10.5306/wjco.125097]

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