Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage

doi:10.5306/wjco.125097

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World Journal of Clinical Oncology

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2218-4333

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World J Clin Oncol. Oct 24, 2026; 17(10): 125097
Published online Oct 24, 2026. doi: 10.5306/wjco.125097

Table 3 Lymph node burden among defined subgroups of poorly cohesive carcinoma, n (%)

		SRC	SRC/PCC-NOS	PCC-NOS	P value
Total examined LNs, n		1624	4327	3434
Examined LNs per case, n		23.20	25.30	25.82
Examined LNs, n	D1	1147	2964	2293
	D2	253	736	660
	D3	224	627	481
Total Metastatic LNs		192 (11.8)	1349 (31.2)	1053 (30.7)
Metastatic LNs	D1	159 (13.9)	1004 (33.9)	790 (34.5)	0.0018
	D2	13 (5.1)	159 (21.6)	154 (23.3)
	D3	20 (8.9)	186 (29.7)	109 (22.7)
Metastatic LNs	N1	9 (7.4)	37 (7.4)	26 (7.0)	< 0.001
	N2	37 (20.9)	94 (16.4)	149 (22.8)
	N3	127 (46.2)	1115 (65.7)	784 (59.6)
Metastatic LNs per case, n	N1	1.50	1.68	1.63
	N2	5.28	3.76	5.52
	N3	10.58	16.16	16

SRC: Signet ring carcinoma; PCC-NOS: Poorly cohesive carcinoma-not otherwise specified; LNs: Lymph nodes.

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Citation: Zheng YH, Wang YY, Wang SC, Wang CJ, Shen YY, Cui JZ, Liu SM, Zhang YH, Zeng XQ, Zhao EH. Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage. World J Clin Oncol 2026; 17(10): 125097
URL: https://www.wjgnet.com/2218-4333/full/v17/i10/125097.htm
DOI: https://dx.doi.org/10.5306/wjco.125097

Zheng YH, Wang YY, Wang SC, Wang CJ, Shen YY, Cui JZ, Liu SM, Zhang YH, Zeng XQ, Zhao EH. Clinicopathological, immunohistochemical, and overall-survival associations of poorly cohesive gastric carcinoma stratified by signet ring cell percentage. World J Clin Oncol 2026; 17(10): 125097 [DOI: 10.5306/wjco.125097]

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