Clinical efficacy of integrated Chinese-Western medicine therapy for metastatic colorectal cancer

doi:10.5306/wjco.124301

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World Journal of Clinical Oncology

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2218-4333

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Oct 24, 2026; 17(10): 124301
Published online Oct 24, 2026. doi: 10.5306/wjco.124301

Table 4 Interaction analysis

Subgroup	HR	95%CI	P value	P for interaction
Sex (male)	0.528	0.296-0.941	0.030	0.003
Sex (female)	1.676	1.014-2.770	0.044	0.003
Gene type (wild type)	0.467	0.236-0.922	0.028	0.005
Gene type (mutant)	1.463	0.989-2.163	0.057	0.005
Prior treatment (third-line or later)	2.175	1.389-3.407	0.001	0.005
TCM deficiency - liver qi stagnation with spleen deficiency	0.465	0.244-0.887	0.020	0.014
KPS < 80	2.492	1.317-4.717	0.005	0.058

HR: Hazard ratio; CI: Confidence interval; TCM: Traditional Chinese medicine; KPS: Karnofsky performance status.

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Citation: Li R, Xu YY, Wu BB, Wang MM, Guan L, Li BR, Wang YW, Yang YF, Pang B. Clinical efficacy of integrated Chinese-Western medicine therapy for metastatic colorectal cancer. World J Clin Oncol 2026; 17(10): 124301
URL: https://www.wjgnet.com/2218-4333/full/v17/i10/124301.htm
DOI: https://dx.doi.org/10.5306/wjco.124301

Li R, Xu YY, Wu BB, Wang MM, Guan L, Li BR, Wang YW, Yang YF, Pang B. Clinical efficacy of integrated Chinese-Western medicine therapy for metastatic colorectal cancer. World J Clin Oncol 2026; 17(10): 124301 [DOI: 10.5306/wjco.124301]

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