Ferritin as a novel predictive index for nasopharyngeal carcinoma survival and therapeutic efficacy of different chemotherapy regimens

Table 5 Association of Ferritin index-related indicator with 3-year mortality (Cox regression)

Variable	Model 1		Model 2		Model 3
	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
Continuous Ferritin value	0.99 (0.99-0.99)	< 0.001a	1.00 (1.00-1.00)	0.058	1.03 (1.02-1.03)	< 0.001a
Ferritin quartile
1	1.00 (reference)		1.00 (reference)		1.00 (reference)
2	0.49 (0.35-0.67)	< 0.001a	0.42 (0.27-0.65)	< 0.001a	0.25 (0.11-0.60)	0.002a
3	0.54 (0.39-0.76)	< 0.001a	0.60 (0.39-0.92)	0.019a	0.58 (0.27-1.22)	0.151
4	0.55 (0.39-0.77)	< 0.001a	0.58 (0.37-0.91)	0.018a	399.19 (175.20-909.51)	< 0.001a

^aP < 0.05.

Model 1: Crude. Model 2: Adjusted for age and sex. Model 3: Adjusted for age, sex, tumor stage, tumor associated material, tumor supplied group of factors, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, gamma-glutamyl transferase, glycyl-proline-dipeptidyl aminopeptidase, and neuron-specific enolase levels. HR: Hazard ratio.