Prognostic significance of PD-L1/PD-1 co-expression and CXCR3-driven inflammatory signatures in Egyptian patients with lymphoproliferative neoplasms

Figure 4 Kaplan-Meier curves for overall survival by biomarker levels in patients with lymphoproliferative neoplasms (n = 90). Eight panels (4 grid × 2 grid) show overall survival curves for low (n = 45, blue) vs high (n = 45, red) levels of the systemic immune-inflammation index, systemic inflammation response index, programmed death-ligand 1/C-X-C motif chemokine receptor 3 (CXCR3), programmed cell death protein 1/CXCR3, CXCR3/T lymphocytes, CXCR3/intermediate monocytes, CXCR3/classical monocytes, and CXCR3/non-classical monocytes. Log-rank P-values and χ² statistics are annotated, with risk tables showing the number at risk over time. OS: Overall survival; SII: Systemic immune-inflammation index; SIRI: Systemic inflammation response index; PD-L1: Programmed death-ligand 1; CXCR3: C-X-C motif chemokine receptor 3; PD-1: Programmed cell death protein 1.