Lynch syndrome association and clinicopathological features in early-onset colorectal cancers: A single-center retrospective study

Table 1 Descriptive statistics and clinical features of the entire study population are summarized, n (%)

Descriptive and clinical features
Age group, median (IQR)	44 (10)
21-30	5 (3.8)
31-40	43 (32.8)
41-50	83 (63.4)
Sex
Male	70 (53.4)
Female	61 (46.6)
Survey (month), median (IQR)	44.5 (44.7)
Tumor diameter (cm), median (IQR)	5 (2.5)
Multiple colorectal tumor
Negative	127 (96.9)
Positive	4 (3.1)
Right colon and transvers colon
Negative	81 (60.0)
Positive	54 (40.0)
Left colon and sigmoid colon
Negative	90 (66.6)
Positive	45 (33.3)
Rectosigmoid colon and rectum
Negative	99 (73.3)
Positive	36 (26.6)
Differentiation degree
Well and moderately	106 (81.5)
Poor	24 (18.5)
Adenocarcinoma component in the tumor
Negative	6 (4.6)
Positive	125 (95.4)
Musinous component in the tumor
Negative	92 (70.2)
Positive	39 (29.8)
Signet-ring cell carcinoma component in the tumor
Negative	122 (93.1)
Positive	9 (6.9)
Lymphovascular invasion
Negative	73 (55.7)
Positive	58 (44.3)
Perineural invasion
Negative	90 (68.7)
Positive	41 (31.3)
Recurrens1
Negative	103 (78.6)
Positive	28 (21.4)
2nd tumor
Negative	120 (91.6)
Positive	11 (8.4)
Family history
Negative	44 (52.4)
Positive	40 (47.6)
LN invasion
Negative	73 (56.5)
Positive	58 (43.5)
T stage
T1	1 (0.8)
T2	9 (6.9)
T3	81 (61.8)
T4a ve T4b	40 (30.5)
N stage
N0	64 (48.9)
N1a, N1b ve N1c	40 (30.5)
N2a ve N2b	27 (20.6)
Metastasis
Negative	99 (75.6)
Positive	32 (24.4)
Stage
1	8 (6.1)
2	48 (37.4)
3	43 (32.8)
4	32 (23.7)
Number of positive LNs, median (IQR)	0 (3)
Number of LNs removed, median (IQR)	20.5 (17)

¹Patients with postoperative metastasis were accepted as relapsed.

IQR: Interquartile range; LN: Lymph node.