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©The Author(s) 2025.
World J Clin Oncol. Aug 24, 2025; 16(8): 108906
Published online Aug 24, 2025. doi: 10.5306/wjco.v16.i8.108906
Published online Aug 24, 2025. doi: 10.5306/wjco.v16.i8.108906
Table 1 2019 World Health Organization Classification and grading criteria for colorectal neuroendocrine neoplasms
Category | Subtype | Differentiation | Grade | Ki67, % | Mitotic rate (/10HPF) |
NET | NET G1 | Well | G1 | < 3 | < 2 |
NET G2 | Well | G2 | 3-20 | 2-20 | |
NET G3 | Well | G3 | > 20 | > 20 | |
NEC | Small cell | Poor | G3 | > 20 | > 20 |
Large cell | Poor | G3 | > 20 | > 20 | |
MiNEN | Well/poor | G1–G3 | Any | Any |
- Citation: Ma YB, Wang ZJ. Current advances in neuroendocrine neoplasms of the colon and rectum. World J Clin Oncol 2025; 16(8): 108906
- URL: https://www.wjgnet.com/2218-4333/full/v16/i8/108906.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i8.108906