Closure techniques for esophageal reconstruction after total laryngectomy and their impact on fistula formation

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Jul 24, 2025 (publication date) through Aug 22, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Jul 24, 2025; 16(7): 109246
Published online Jul 24, 2025. doi: 10.5306/wjco.v16.i7.109246

Table 4 Analysis of factors influencing fistula formation

Variable	OR	95%CI	P value
Type of anastomosis (hand-sewn vs stapler)	4.08	1.33-12.52	0.014
Pre-RTH	3.65	1.21-10.97	0.021
Pre-CHTH	1.22	0.62-2.85	0.551
Age	1.08	0.82-1.42	0.232
Sex (male vs female)	0.94	0.51-1.84	0.719

OR: Odds ratio; Pre-CHTH: Pre-surgical chemotherapy; Pre-RTH: Pre-surgical radiotherapy.

Citation: Galazka A, Stawarz K, Bienkowska-Pluta K, Paszkowska M, Misiak-Galazka M. Closure techniques for esophageal reconstruction after total laryngectomy and their impact on fistula formation. World J Clin Oncol 2025; 16(7): 109246
URL: https://www.wjgnet.com/2218-4333/full/v16/i7/109246.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i7.109246