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©The Author(s) 2025.
World J Clin Oncol. Jul 24, 2025; 16(7): 108666
Published online Jul 24, 2025. doi: 10.5306/wjco.v16.i7.108666
Published online Jul 24, 2025. doi: 10.5306/wjco.v16.i7.108666
Figure 7 Nitidine chloride may affect colorectal cancer progression by targeting kinesin family member 20A through regulation of pathways such as mitosis.
A: Venn diagram intersection analysis of highly expressed genes in colorectal cancer (CRC), genes positively correlated with kinesin family member 20A, and downregulated genes after nitidine chloride (NC) treatment of CRC cells; B: Biological function enrichment analysis results of intersection genes; C: Volcano plot of sequencing data after NC treatment of CRC cells. NC: Nitidine chloride; CRC: Colorectal cancer; BP: Biological process; CC: Cellular component; MF: Molecular function; KEGG: Kyoto Encyclopedia of Genes and Genomes.
- Citation: Wu KJ, Zeng DT, He RQ, Li DM, Yao JL, Liu LM, Huang WJ, Qin DY, Li YF, He H, Li SD, Wen JY, Meng L, Shi JR, Chen G, Li H. Nitidine chloride may mediate its antitumor effects by targeting kinesin family member 20A in colorectal cancer cells. World J Clin Oncol 2025; 16(7): 108666
- URL: https://www.wjgnet.com/2218-4333/full/v16/i7/108666.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i7.108666