Demographic trends in mortality due to ovarian cancer in the United States, 1999-2020

Table 3 Annual percent change of ovarian carcinoma-related age-adjusted mortality rates per 100000 in females in the United States, 1999 to 2020

Year interval	APC (95%CI)
Overall
1999-2003	0.41 (-0.48 to 1.79)
2003-2020	-2.28a (-2.39 to -2.16)
NH White
1999-2002	0.66 (-0.49 to 2.36)
2002-2006	-1.34a (-2.67 to -0.60)
2006-2020	-2.4034a (-3.30 to -1.95)
NH Black or African American
1999-2002	1.16 (-1.48 to 6.05)
2002-2020	-1.71a (-3.26 to -1.46)
NH American Indian or Alaska Native
1999-2020	-1.00 (-2.18 to 0.42)
Hispanic or Latino
1999-2005	0.30 (-1.10 to 5.47)
2005-2020	-1.72a (-2.77 to -1.41)
NH Asian or Pacific Islander
1999-2020	-0.85a (-1.16 to -0.46)
Young aged (25-44 years)
1999-2020	-1.83a (-2.20 to -1.46)
Middle aged (45-64 years)
1999-2020	-2.17a (-2.41 to -1.92)
Old aged (65 to > 85 years)
1999-2001	2.31 (-0.09 to 4.28)
2001-2007	-0.90a (-2.80 to -0.45)
2007-2020	-2.88a (-3.12 to -2.67)
Non-metropolitan areas
1999-2004	0.50 (-0.56 to 2.55)
2004-2020	-2.20a (-2.47 to -1.98)
Metropolitan areas
1999-2003	0.27 (-0.69 to 1.79)
2003-2020	-2.31a (-2.45 to -2.19)
Northeast region
1999-2002	1.15 (-0.84 to 4.52)
2002-2020	-2.39a (-2.60 to -2.22)
Midwest region
1999-2003	0.62 (-0.85 to 3.62)
2003-2020	-2.37a (-2.64 to -2.17)
South region
1999-2005	-0.37 (-1.02 to 0.81)
2005-2020	-2.29a (-2.50 to -2.11)
West region
1999-2004	0.12 (-0.51 to 1.09)
2004-2008	-3.18a (-4.24 to -2.32)
2008-2016	-1.64a (-1.93 to -0.29)
2016-2020	-3.58a (-5.02 to -2.76)

^aP value < 0.05, statistically significant annual percent change values.

APC: Annual percent change; CI: Confidence interval; NH: Non-Hispanic.