Clinical significance of the transcription factor (SOX11) expression in the bone marrow of acute myeloid leukemia patients

Table 2 Association between SOX expression and clinical patient features

Assessed parameters	Value	SOX11 expression	P value
Sex	Male	0.1 (0-81.6)	0.797
	Female	0.03 (0-106)
CD34	Negative	0.05 (0-106)	0.607
	Positive	0.105 (0-105)
FLT3 ITD	Negative	0.005 (0-5.9)	P < 0.001
	Positive	0.09 (0-2.4)
NPM	Negative	0.11 (0-105)	0.166
	Positive	0.01 (0-9.5)
Liver	Negative	0.055 (0-106)	0.928
	Positive	0.09 (0-5.8)
Spleen	Negative	0.06 (0-106)	0.599
	Positive	0.05 (0-5.86)
LNs	Negative	0.05 (0-106)	0.953
	Positive	0.21 (0-5.86)
BM celularity	Hypocellular	0.09 (0-2.1)	0.268
	Normocellular	0.03 (0-82.5)
	Hypercellular	0.11 (0-106)
FAB	AML-M1	0.02 (0-106)	0.008
	AML-M2	0.35 (0-105)
	AML-M3	0.115 (0-0.21)
	AML-M4	0.015 (0-10.9)
	AML-M5	0 (0-2.9)
Cytogenetic	Normal	0.01 (0-5.9)	0.011
	Abnormal	0.1 (0-2.4)
CR	Negative	0.055 (0-6.19)	0.806
	Positive	0.145 (0-81.57)
Relapse/refractory	Negative	0.08 (0-10.9)	0.702
	Positive	0.12 (0-81.6)
Death	Negative	0.14 (0-10.9)	0.593
	Positive	0.085 (0-81.6)
Age	SOX low expression	44 (18-70)	0.784
	SOX over expression	43 (18-78)
Hb	SOX low expression	7.2 (2-14)	0.122
	SOX over expression	7.6 (5-14)
PLT	SOX low expression	47.5 (4-836)	0.921
	SOX over expression	46 (8-420)
TLC	SOX low expression	61530 (1150-387900)	0.058
	SOX over expression	30600 (1120-488900)
PB blast	SOX low expression	31 (0-97)	0.206
	SOX over expression	30 (0-97)
BM blast	SOX low expression	50 (0-98)	0.516
	SOX over expression	50 (0-96)
D14 blasts	SOX low expression	0 (0-77)	0.243
	SOX over expression	0 (0-80)
D28 blasts	SOX low expression	0 (0-53)	0.289
	SOX over expression	0 (0-80)

TLC: Total leukocyte count; PLT: Platelet counts; AML: Acute myeloid leukemia; BM: Bone marrow; CR: Complete remission; Hb: Hemoglobin; LNs: Lymph nodes; PB: Peripheral blood.