Inclusion criteria for liver transplantation in patients with colorectal liver metastases: How to make the best selection?

Table 3 Characteristics of the Oslo, Fong, and Eastern Cooperative Oncology Group scoring systems

Score	Component	Scoring/criteria	Cutoff	Clinical interpretation
Oslo	Tumor size	> 5.5 cm = 1 point	≥ 2 points	Higher recurrence risk post-LT
	CEA level	> 80 ng/mL = 1 point
	Time from primary to LT	< 2 years = 1 point
	Response to chemotherapy	< 10% shrinkage = 1 point
Fong	Nodal status of primary	Positive = 1 point	≥ 3 points	Worse prognosis post-resection
	Disease-free interval	< 12 months = 1 point
	Number of liver metastases	> 1 = 1 point
	CEA level	> 200 ng/mL = 1 point
	Largest tumor	> 5 cm = 1 point
ECOG	Performance status	0 = fully active; 1 = symptomatic but completely ambulatory; 2 = symptomatic, < 50% in bed during the day; 3 = symptomatic, > 50% in bed, but not bedbound; 4 = bedridden	≥ 2 = ineligible	Stratifies fitness for treatment or surgery

ECOG: Eastern Cooperative Oncology Group; LT: Liver transplantation; CEA: Carcinoembryonic antigen.