Predictors of survival in gastric mucosa-associated lymphoid tissue lymphoma: An updated surveillance, epidemiology, and end results-based analysis of age and gender disparities

Table 3 Multivariate cox proportional hazard regression analyses of factors affecting all-cause mortality and cancer related mortality among United States patients diagnosed with mucosa-associated lymphoid tissue lymphoma between 2010 and 2021¹

Characteristics	Overall Mortality. Adjusted proportional. Hazard ratio (95%CI)	Cancer related mortality. Adjusted proportional. Hazard ratio (95%CI)
Race
NH-White	1 (reference)	1 (reference)
NH-Black	1.28 (0.98-1.67)	1.54 (0.89-2.67)
Hispanic	0.94 (0.71-1.25)	1.13 (0.65-1.99)
Other	0.88 (0.62-1.26)	2.18 (1.24-3.83)b
Gender
Female	1 (reference)	1 (reference)
Male	1.61 (1.33-1.93)b	1.54 (1.04-2.27)a
Age at diagnosis (years)
0-39	1 (reference)	1 (reference)
40-59	1.18 (0.58-2.37)	1.31 (0.30-5.82)
60-79	2.75 (1.40-5.41)b	3.19 (0.76-13.39)
80+	9.23 (4.62-18.46)b	12.53 (2.88-54.51)b
Marital status
Married	1 (reference)	1 (reference)
Single	1.62 (1.25-2.08)b	1.86 (1.14-3.02)a
Divorced/separated	1.93 (1.46-2.55)b	1.60 (0.86-2.98)
Widowed	1.64 (1.28-2.11)b	1.16 (0.67-2.02)
Tumor stage
Localized	1 (reference)	1 (reference)
Regional	1.10 (0.82-1.47)	1.97 (1.16-3.36)a
Distant	1.78 (1.34-2.35)b	4.74 (2.93-7.68)b
Living area
Counties in metropolitan areas of 1 million persons	1 (reference)	1 (reference)
Counties in metropolitan areas of 250000 to 1 million persons	1.04 (0.84-1.30)	0.86 (0.54-1.39)
Counties in metropolitan areas of 250000 persons	0.99 (0.68-1.43)	0.56 (0.21-1.52)
Nonmetropolitan counties adjacent to a metropolitan area	0.72 (0.45-1.15)	0.85 (0.32-2.25)
Nonmetropolitan counties not adjacent to a metropolitan area	0.68 (0.40-1.15)	0.54 (0.16-1.90)
Income per year
< $40000	1 (reference)	1 (reference)
$40000-59999	0.35 (0.19-0.67)b	0.42 (0.10-1.78)
$60000-79999	0.29 (0.15-0.56)b	0.34 (0.08-1.49)
$80000-99999	0.27 (0.14-0.53)b	0.31 (0.07-1.42)
$100000+	0.23 (0.11-0.47)b	0.30 (0.06-1.42)
Radiation
No	1 (reference)	1 (reference)
Yes	0.78 (0.64-0.94)b	0.78 (0.52-1.17)
Chemotherapy
No	1 (reference)	1 (reference)
Yes	0.99 (0.76-1.29)	1.47 (0.91-2.39)
Surgery
No	1 (reference)	1 (reference)
Yes	1.10 (0.54-2.23)	0.75 (0.18-3.13)

^aP < 0.05.

^bP < 0.01.

¹Variables included in the multivariate model were age at diagnosis, gender, annual income, marital status, tumor stage, radiation, and chemotherapy.