Navigating the evidence for hepatocellular carcinoma treatment: Surgery vs radiofrequency ablation through sentiment and meta-analysis

Table 6 Summary of meta-analysis of adjusted hazard ratios for recurrence comparing liver resection and radiofrequency ablation

Ref.	Study type	Adjusted HR	95%CI lower	95%CI upper	Weight (%)	Treatment favored	Subgroup
Bai et al[10]	Retrospective comparative study	0.78	0.63	0.97	82.50	Resection	High risk MVI and Milan criteria
Bai et al[10]	Retrospective comparative study	0.51	0.32	0.81	17.81	Resection	High risk MVI e size < 3 cm
Gory et al[13]	Retrospective comparative study	0.48	0.28	3.52	2.42	No difference	< 5 cm
He et al[14]	Retrospective comparative study	0.43	0.31	3.2	2.75	No difference	Total
Liu et al[18]	Retrospective comparative study	0.41	0.26	3.8	2.12	No difference	Total
Qiu et al[22]	Retrospective comparative study	0.63	0.46	2.1	6.56	No difference	Total
Takayasu et al[25]	Retrospective comparative study	0.52	0.35	0.7	24.72	Resection	Total
Zeng et al[31]	Retrospective comparative study	0.43	0.32	0.56	49.07	Resection	Age > 65 years
Zeng et al[31]	Retrospective comparative study	0.57	0.45	0.73	65.65	Resection	Age < 65 years
Zhong et al[32]	Retrospective comparative study	0.68	0.57	0.82	116.19	Resection	Total
Pooled estimate		0.61	0.55	0.68	100	Resection

HR: Hazard ratio; CI: Confidence interval; MVI: Microvascular invasion.