Navigating the evidence for hepatocellular carcinoma treatment: Surgery vs radiofrequency ablation through sentiment and meta-analysis

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May 24, 2025 (publication date) through May 19, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Clin Oncol. May 24, 2025; 16(5): 105881
Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.105881

Table 5 Meta-analysis summary (overall survival)

Statistic	Value
Number of studies reviewed	23
Number of studies included in meta-analysis	11
Pooled hazard ratio	0.5924
95% confidence interval for hazard ratio	0.5404-0.6493
Heterogeneity (I²)	39.98%
Cochran’s Q statistic	21.66
P value for heterogeneity	0.0608
Model used	Random effects
Significance threshold	HR < 1 favors liver resection

HR: Hazard ratio.

Citation: Cicerone O, Mantovani S, Oliviero B, Basilico G, Corallo S, Quaretti P, Maestri M. Navigating the evidence for hepatocellular carcinoma treatment: Surgery vs radiofrequency ablation through sentiment and meta-analysis. World J Clin Oncol 2025; 16(5): 105881
URL: https://www.wjgnet.com/2218-4333/full/v16/i5/105881.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i5.105881