Helicobacter pylori infection promotes the progression of gastric cancer by regulating the expression of DMBT1

doi:10.5306/wjco.v16.i5.105322

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May 24, 2025 (publication date) through Jun 7, 2025

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. May 24, 2025; 16(5): 105322
Published online May 24, 2025. doi: 10.5306/wjco.v16.i5.105322

Table 3 Comparison of relative proliferative capacities in each group

Group	mean ± SD	vs group	95%CI	F	η²
Control	0.68 ± 0.05^b^,^c^,^d	H. pylori	-0.20 to -0.09	47.84	0.878
		si-DMBT1	-0.25 to -0.14
		H. pylori + si-DMBT1	-0.38 to -0.27
H. pylori	0.82 ± 0.06^a^,^d	si-DMBT1	-0.11 to 0.01
		H. pylori + si-DMBT1	-0.24 to -0.12
si-DMBT1	0.87 ± 0.04^a^,^d	H. pylori + si-DMBT1	-0.19 to -0.07
H. pylori + si-DMBT1	1.00 ± 0.03^a^,^b^,^c

^aP < 0.05 vs control group.

^bP < 0.05 vs Helicobacter pylori group.

^cP < 0.05 vs si-DMBT1 group.

^dP < 0.05 vs Helicobacter pylori + si-DMBT1 group.

H. pylori: Helicobacter pylori; DMBT1: Deleted in malignant brain tumors 1; CI: Confidence interval.

Citation: Zhou X, Wang LQ, Song S, Xu M, Li CP. Helicobacter pylori infection promotes the progression of gastric cancer by regulating the expression of DMBT1. World J Clin Oncol 2025; 16(5): 105322
URL: https://www.wjgnet.com/2218-4333/full/v16/i5/105322.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i5.105322