Role of cell cycle-related gene SAC3 domain containing 1 as a potential target of nitidine chloride in hepatocellular carcinoma progression

Figure 5 Impact of SAC3 domain containing 1 knockdown on cell proliferation, invasion and migration. A: SAC3 domain containing 1 (SAC3D1) knockdown efficiency detection (real-time reverse transcriptase-polymerase chain reaction); B: Knockdown of SAC3D1 significantly inhibited proliferation of hepatocellular carcinoma (HCC) cells; C: Knockdown of SAC3D1 dramatically decreased the invasion and migration of HCC cells. ^aP < 0.05, ^cP < 0.001, ^dP < 0.001. NC: Nitidine chloride; SAC3D1: SAC3 domain containing 1.