Functional heterogeneity and clinical implications of CD4+ T cell subtypes in high-grade serous ovarian carcinoma

Figure 3 Differential distribution and functional profiling of regulatory T cell subtypes in adnexa and ascites. A: Marker gene ranking for CD4+ Treg subtypes; B: UMAP plots illustrating the expression of key marker genes across CD4+ Treg subtypes; C: Correlation heatmap of CD4+ T cell subtypes between adnexal tissues and ascites; D: UMAP visualization of CD4+ Treg subtypes; E: Density distribution of Treg cells in adnexa and ascites; F: Proportional distribution of CD4+ Treg subtypes in adnexa and ascites; G: UMAP visualization of exhaustion and activation marker expression in Treg cells; H: Heatmap of key transcriptional regulators and marker expression across Treg subtypes; I: Expression levels and group distribution of exhaustion markers in Treg cells across adnexa and ascites; J: Exhaustion marker expression across Treg subtypes.