Endoscopic submucosal dissection and hybrid endoscopic submucosal dissection for stage 1 rectal neuroendocrine tumors

Table 3 Follow-up of the 12 non-curable resection cases

Number	Gender	Age	Size (mm)	Method	Grade	Invasion depth	Salvage therapy	Microscopic examination	Follow-up (month)	Recurrence
1	Male	41	10	ESD	G1	Submucosa	Colonoscopy	/	76	No
2	Female1	20	5	hybrid ESD	G1	Submucosa	Colonoscopy	/	30	No
3	Male	34	10	ESD	G1	Submucosa	Salvage local resection	Negative	24	No
4	Female	46	8	ESD	G1	Submucosa	Salvage radical surgery	Negative	16	No
5	Female	32	6	hybrid ESD	G1	Submucosa	Colonoscopy	/	12	No
6	Male	27	10	ESD	G1	Submucosa	Salvage local resection	Negative	34	No
7	Female	51	15	hybrid ESD	G1	Submucosa	Colonoscopy + biopsy	Negative	38	No
8	Female	31	8	hybrid ESD	G1	Submucosa	Colonoscopy + biopsy	Negative	25	No
9	Male	53	5	ESD	G1	Submucosa	Colonoscopy	/	20	No
10	Male	35	4	ESD	G1	Submucosa	Colonoscopy + biopsy	Negative	29	No
11	Male	36	10	ESD	G1	Submucosa	Colonoscopy + biopsy	Negative	15	No
12	Male	55	5	ESD	G1	Submucosa	Colonoscopy + biopsy	Negative	10	No

¹The case had vascular invasion, and the other 11 cases had positive vertical margins.

Colonoscopy: Colonoscopy follow-up without mucosal biopsy; Colonoscopy + biopsy: Colonoscopy follow-up with mucosal biopsy; ESD: Endoscopic submucosal dissection.